The University of Illinois NeuroRepository

Focusing Big Data into Cures

A one-of-a-kind human brain tissue bank and research database that links clinical, radiological, physiological, histological, and molecular data to thousands of tissue samples and makes it AI-Ready.

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Our Focus

Data integration adds value to human brain tissue

The University of Illinois NeuroRepository is a one-of-a-kind human brain tissue bank and research database that fuels innovative research and cures for brain disorders. The NeuroRepository is unique because it takes a ‘big data’ approach to link clinical, radiological, physiological, histological, and molecular/genomic data to thousands of human tissue samples and makes it 'AI-Ready'. Initiated in 2017, the NeuroRepository provides unsurpassed value to the research community and producing important new discoveries for those with neurological and psychiatric disorders.

Our discovery pipeline

Integrative multi-omics data linked to brain tissue

What We Do

Collaborative, disease- and location-specific brain tissue repositories

Home-grown neuroinformatics tools enrich our tissue and data reserves because to take full advantage of AI, you need good data.

Epilepsy

Thousands of surgical brain samples meticulously linked to imaging, in vivo recordings, and clinical data through our Intuition platform.

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ALS

A rapid autopsy program collecting tissue within 3 hours of death, revealing new links between brain, spinal cord, and nerve injury.

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Brain Tumors

Spatially linked tissue sampling connecting imaging, histology, genomics, and clinical data across a federated network.

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Other Programs

Blood-Brain Barrier, Multiple Sclerosis, vascular malformations, and Alzheimer’s Disease.

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Our Platform

Integrated AI-Ready data through Intuition

Intuition is our neuroinformatics hub generating powerful integrative datasets from home-grown software that harmonizes every data type against the tissue it came from.

Intuition - Epilepsy Surgery
Intuition - Rare Disease
Intuition - NeuroICU
Intuition - NeuroPsych

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Scientific Cores

The engines behind the discovery

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Integrative Multi-Omics

Genomics, gene expression, proteomics, and metabolomics linked to imaging, electrical signaling, histology, and clinical data led by Fabien Dachet, PhD.

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Computational Neuroscience

Signal processing and quantitative image analysis of the brain’s complex networks and systems development led by Biswajit Maharathi, PhD powering Intuition and ADRESai.

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Human Tissue Laboratory

Meticulous collection and processing that keeps every sample research-grade and clinically linked led by Fozia Mir, PhD.

Giving Back Through Clinical Translation

Science with purpose, medicine with meaning

The best way to translate our work into meaningful results for patients and families is to commercialize discoveries through intellectual property, copyrighted software, and AI-ready datasets. Our commercialization trajectories include new drugs and biomarkers for epilepsy, a new drug for ALS and Alzheimer’s, the Intuition platform, and a new MRI biomarker for epileptic activity.

Meet our team

Collaborate with the NeuroRepository

We are eager to work with academic and industry researchers to take full advantage of our human tissue bank, disease-specific AI-ready datasets, and software tools — with a strong pipeline of novel biomarkers and therapeutics moving toward the clinic.

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